TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss
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DOI: 10.1016/j.neuron.2017.05.037
Abstract: Summary Microglia coordinate various functions in the central nervous system ranging from removing synaptic connections, to maintaining brain homeostasis by monitoring neuronal function, and clearing protein aggregates across the lifespan. Here we investigated whether increased… read more here.
Keywords: tdp depletion; microglia; synapse loss; pathology ... See more keywords