Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
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DOI: 10.1093/brain/awz099
Abstract: Nelson et al. describe a recently recognized brain disorder that mimics the clinical features of Alzheimer’s disease: Limbic-predominant Age-related TDP-43 Encephalopathy (LATE). They review the literature and present consensus-based recommendations of an international, multidisciplinary working… read more here.
Keywords: related tdp; age related; predominant age; encephalopathy late ... See more keywords
Limbic-Predominant Age-Related TDP-43 Encephalopathy
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DOI: 10.1212/wnl.0000000000200001
Abstract: Background and Objectives Limbic-predominant age-related Tar DNA binding protein 43 (TDP-43) encephalopathy neuropathologic change (LATE-NC) is present in ≈25% of older persons' brains and is strongly associated with cognitive impairment. Hippocampal sclerosis (HS) pathology is… read more here.
Keywords: age related; limbic predominant; pathology; predominant age ... See more keywords