TDP43 pathology in the brain, spinal cord, and dorsal root ganglia of a patient with FOSMN
Sign Up to like & getrecommendations! Published in 2019 at "Neurology"
DOI: 10.1212/wnl.0000000000007008
Abstract: Objective To describe the histopathologic features of a case of facial-onset sensory and motor neuronopathy (FOSMN). Methods We describe a postmortem examination performed on a 54-year-old man with FOSMN associated with personality change. Results Postmortem… read more here.
Keywords: tdp43 pathology; fosmn; tdp43; pathology ... See more keywords
TDP43 Exacerbates Atherosclerosis Progression by Promoting Inflammation and Lipid Uptake of Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.687169
Abstract: Objective Atherosclerosis (AS), characterized by cholesterol overloaded-macrophages accumulation and plaque formation in blood vessels, is the major cause of cardiovascular disease. Transactive response DNA-binding proteinā¼43 kDa (TDP43) has recently been identified as an independent driver… read more here.
Keywords: uptake macrophages; response; dna; tdp43 ... See more keywords