TDRD3 promotes DHX9 chromatin recruitment and R-loop resolution
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab642
Abstract: Abstract R-loops, which consist of a DNA/RNA hybrid and a displaced single-stranded DNA (ssDNA), are increasingly recognized as critical regulators of chromatin biology. R-loops are particularly enriched at gene promoters, where they play important roles… read more here.
Keywords: dhx9 chromatin; tdrd3 promotes; loop; gene ... See more keywords
TDRD3 is an antiviral restriction factor that promotes IFN signaling with G3BP1
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010249
Abstract: Stress granules (SGs) are highly dynamic cytoplasmic foci that form in response to activation of the integrated stress response (ISR) that results in eIF2α phosphorylation and global translation shutdown. Stress granules, which are largely nucleated… read more here.
Keywords: tdrd3 antiviral; g3bp1; tdrd3; evidence tdrd3 ... See more keywords