Immunotherapy in Prostate Cancer: Teaching an Old Dog New Tricks
Sign Up to like & getrecommendations! Published in 2018 at "Current Oncology Reports"
DOI: 10.1007/s11912-018-0712-z
Abstract: Immunotherapy is rapidly transforming cancer care across a range of tumor types. Although Sipuleucel-T represented the first successful vaccine for the treatment of established cancer, other immunotherapeutic approaches for prostate cancer such as checkpoint inhibitors… read more here.
Keywords: cancer teaching; prostate cancer; immunotherapy prostate; teaching old ... See more keywords
Teaching an old dog new tricks: repurposing β-lactams.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2021.06.003
Abstract: Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative route to defeat drug-resistant strains… read more here.
Keywords: repurposing lactams; dog new; new tricks; tricks repurposing ... See more keywords
The hackers teaching old DNA sequencers new tricks
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-05769-8
Abstract: Outdated genome-sequencing machines need not die — researchers can repurpose them to drive next-generation biochemistry studies.Outdated DNA-sequencing machines need not die — researchers can repurpose them to drive next-generation biochemistry studies. read more here.
Keywords: biochemistry; sequencers new; dna sequencers; hackers teaching ... See more keywords
Teaching an old dog new tricks: next-generation CAR T cells
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Cancer"
DOI: 10.1038/s41416-018-0325-1
Abstract: Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for… read more here.
Keywords: cell therapy; act; car; teaching old ... See more keywords
Teaching an old antibody response new tricks
Sign Up to like & getrecommendations! Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aax1716
Abstract: The human antibody repertoire against influenza virus is shaped by prior infection and vaccination. The human antibody repertoire against influenza virus is shaped by prior infection and vaccination. read more here.
Keywords: new tricks; old antibody; antibody; response new ... See more keywords