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Published in 2017 at "Neurochemical Research"
DOI: 10.1007/s11064-017-2390-x
Abstract: Spatiotemporally ordered production of cells is essential for brain development. Normally, most undifferentiated neural progenitor cells (NPCs) face the apical (ventricular) surface of embryonic brain walls. Pathological detachment of NPCs from the apical surface and…
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Keywords:
neural progenitor;
progenitor cells;
tead;
yap tead ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3401
Abstract: The Hippo pathway is an evolutionarily conserved signaling cascade. Its dysregulation may lead to cancer progression, metastasis, cancer therapy resistance, and immune evasion. Diverse genetic aberrations leading to YAP/TAZ hyperactivation have been elucidated over the…
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Keywords:
tead;
gh658;
gh658 novel;
cancer therapy ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4976
Abstract: Pharmacological inhibitors of TEAD transcription factors have emerged as a promising novel class of anti-cancer agents. TEAD inhibitors disrupt oncogenic YAP/TAZ signaling, resulting in cell cycle arrest and cell death in susceptible cancers. In preclinical…
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Keywords:
anti cancer;
tead;
activity;
bgi 9004 ... See more keywords
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Published in 2023 at "Plants"
DOI: 10.3390/plants12010206
Abstract: Atriplex dimorphostegia (Saltbush) is an annual halophytic shrub that is widely distributed across various parts of Asia. The current study is the first to report the metabolites profile of the total ethanol extract of the…
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Keywords:
uplc pda;
tead;
silico vivo;
anabolic effect ... See more keywords