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TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC

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Published in 2023 at "Pharmaceuticals"

DOI: 10.3390/ph16040553

Abstract: KRASG12C is one of the most common mutations detected in non-small cell lung cancer (NSCLC) patients, and it is a marker of poor prognosis. The first FDA-approved KRASG12C inhibitors, sotorasib and adagrasib, have been an… read more here.

Keywords: cell; krasg12c inhibitors; krasg12c; mutant nsclc ... See more keywords