RBFOX2-regulated TEAD1 alternative splicing plays a pivotal role in Hippo-YAP signaling
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac509
Abstract: Abstract Alternative pre-mRNA splicing is key to proteome diversity; however, the biological roles of alternative splicing (AS) in signaling pathways remain elusive. Here, we focus on TEA domain transcription factor 1 (TEAD1), a YAP binding… read more here.
Keywords: rbfox2 regulated; tead1; alternative splicing; yap ... See more keywords
PO-125 FAT1 on salvador-warts-hippo (SWH) pathway in human glioblastoma
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DOI: 10.1136/esmoopen-2018-eacr25.166
Abstract: Introduction Glioblastoma(GBM) is an aggressive brain tumour arising from glial cells. Our lab has identified the oncogenic role of FAT1 gene in GBM, regulating inflammatory and hypoxic microenvironment of the tumour as well as migratory/invasive… read more here.
Keywords: yap1; fat1; tead1; salvador warts ... See more keywords
CircSLC8A1 Exacerbates Hypoxia-Induced Myocardial Injury via Interacting with MiR-214-5p to Upregulate TEAD1 Expression.
Sign Up to like & getrecommendations! Published in 2022 at "International heart journal"
DOI: 10.1536/ihj.21-547
Abstract: Circular RNAs (circRNAs) act as important regulators in myocardial infarction (MI). This study aimed to explore the regulatory mechanism of circRNA solute carrier family 8 member A1 antisense RNA 1 (circSLC8A1) in hypoxia-induced myocardial injury.Exosomes… read more here.
Keywords: hypoxia induced; tead1; circslc8a1; mir 214 ... See more keywords