Development of a HPLC-MS/MS method for assessment of thiol redox status in human tear fluids.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114295
Abstract: Oxidative stress is reported to be part of the pathology of many ocular diseases. For the diagnosis of ocular diseases, tear fluid has unique advantages. Although numerous analytical methods exist for the measurement of different… read more here.
Keywords: tear fluids; thiol redox; hplc method;
MicroRNAs in tear fluids predict underlying molecular changes associated with Alzheimer’s disease
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DOI: 10.26508/lsa.202201757
Abstract: This study demonstrated the translational potential of deregulated tear fluid miRNAs associated with amyloid beta production and proinflammation in a transgenic AD mouse model. Extracellular circulating microRNAs (miRNAs) have been discussed as potential biomarkers for… read more here.
Keywords: disease; alzheimer disease; mirnas associated; expression levels ... See more keywords
Metabolomic Alterations in the Tear Fluids of Patients With Superior Limbic Keratoconjunctivitis
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DOI: 10.3389/fmed.2021.797630
Abstract: Purpose Superior limbic keratoconjunctivitis (SLK) is a bilateral, chronic inflammatory disease that recurs for up to several years; however, the fundamental processes involved in its pathogenic mechanisms remain unknown. We aimed to investigate the metabolomic… read more here.
Keywords: metabolomic alterations; superior limbic; alterations tear; tear fluids ... See more keywords