Emerging targets of inflammation and tear secretion in dry eye disease.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.02.006
Abstract: The underlying mechanisms of dry eye are thought to be part of a vicious circle involving a hyperosmolarity-triggered inflammatory cascade, resulting in loss of goblet cells and glycocalyx mucin and observed corneal and conjunctival epithelial… read more here.
Keywords: tear secretion; vicious circle; eye; dry eye ... See more keywords
Short-Term Effects of Ground-Level Ozone in Patients With Dry Eye Disease: A Prospective Clinical Study.
Sign Up to like & getrecommendations! Published in 2019 at "Cornea"
DOI: 10.1097/ico.0000000000002045
Abstract: PURPOSE To investigate changes in the clinical features of patients with dry eye disease (DED) according to short-term outdoor ground-level ozone exposure. METHODS This prospective observational study included patients with DED who were treated with… read more here.
Keywords: dry eye; ground level; short term; tear secretion ... See more keywords
Direct visualization of aqueous tear secretion from lacrimal gland
Sign Up to like & getrecommendations! Published in 2017 at "Acta Ophthalmologica"
DOI: 10.1111/aos.13335
Abstract: To introduce a new method for direct observation of tear secretion from the palpebral lobes of the main lacrimal glands and Wolfring glands using fluorescein dye. read more here.
Keywords: direct visualization; secretion; visualization aqueous; tear secretion ... See more keywords
Peripheral hypertrophic subepithelial corneal opacification – Role of tear secretion, medication and systemic diseases
Sign Up to like & getrecommendations! Published in 2024 at "Acta Ophthalmologica"
DOI: 10.1111/aos.16680
Abstract: Peripheral hypertrophic subepithelial corneal opacification (PHSCO) is a corneal disease that may severely affect vision. The major goal of this study was to test the hypothesis that tear secretion, medication and systemic diseases are associated… read more here.
Keywords: peripheral hypertrophic; tear secretion; secretion medication; hypertrophic subepithelial ... See more keywords
Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0243176
Abstract: Objective To investigate the clinical effects of IRT5 probiotics in the environmental dry eye model. Methods Eight week old male C57BL/6 mice were randomly divided into two groups; control group (n = 16) received oral… read more here.
Keywords: tear secretion; group; irt5 probiotics; experimental dry ... See more keywords
Multicomponent Dietary Supplementation: Impact on Tear Secretion and Ocular Surface Inflammation in Dry Eye Syndrome Patients
Sign Up to like & getrecommendations! Published in 2025 at "Antioxidants"
DOI: 10.3390/antiox14010103
Abstract: Dry eye syndrome (DES) is a prevalent ocular condition characterized by tear film instability, inflammation, and discomfort, affecting millions worldwide. DES is related to oxidative stress imbalance and ocular surface inflammation, which are important factors… read more here.
Keywords: ocular surface; tear secretion; surface inflammation; inflammation ... See more keywords
Restoration of Tear Secretion in a Murine Dry Eye Model by Oral Administration of Palmitoleic Acid
Sign Up to like & getrecommendations! Published in 2017 at "Nutrients"
DOI: 10.3390/nu9040364
Abstract: Sea buckthorn (Hippophae rhamnoides)–derived products have traditionally been used as food and medicinal ingredients in Eastern countries. The purpose of this study was to investigate the effect of oral intake of sea buckthorn oil products… read more here.
Keywords: tear secretion; oil; dry eye; sea buckthorn ... See more keywords