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   Articles with "tecovirimat" as a keyword



Early Tecovirimat Treatment for Mpox Disease Among People With HIV.

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recommendations! Published in 2024 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2023.7696

Abstract: Importance Despite a lack of effectiveness data in humans, tecovirimat was widely prescribed to people with HIV (PWH) with mpox during the 2022 mpox epidemic, particularly PWH with low CD4+ T-cell counts or severe mpox… read more here.

Keywords: tecovirimat group; tecovirimat; early tecovirimat; mpox disease ... See more keywords

Overview of the regulatory approval of tecovirimat intravenous formulation for treatment of smallpox: potential impact on smallpox outbreak response capabilities, and future tecovirimat development potential

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recommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"

DOI: 10.1080/14787210.2023.2170350

Abstract: ABSTRACT Introduction Tecovirimat oral capsule formulation is approved in the US and Canada for treatment of smallpox and in the United Kingdom (UK) and European Union (EU) for treatment of multiple human orthopoxvirus diseases, including… read more here.

Keywords: mpox; formulation; smallpox; development ... See more keywords

Early clinical experience using tecovirimat during the 2022 mpox epidemic in Toronto underscores ongoing clinical equipoise and the need for randomized trials

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recommendations! Published in 2025 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkaf010

Abstract: Abstract Background Tecovirimat is an antiviral drug that was used compassionately for treating mpox in high-income settings during the 2022 global outbreak. Randomized controlled trials of its efficacy have not yet been completed. Objectives To… read more here.

Keywords: underscores ongoing; tecovirimat; clinical equipoise; ongoing clinical ... See more keywords

Association of Tecovirimat Therapy With Mpox Symptom Improvement: A Cross-sectional Study—King County, Washington, May–October 2022

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recommendations! Published in 2024 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofae029

Abstract: Abstract Background Data on tecovirimat effectiveness for human mpox are limited. We conducted a retrospective cross-sectional interview-based study to identify associations between tecovirimat treatment and the mpox clinical course. Methods Using public health surveillance data… read more here.

Keywords: tecovirimat; improvement; symptom improvement; cross sectional ... See more keywords

A Glance at the Development and Patent Literature of Tecovirimat: The First-in-Class Therapy for Emerging Monkeypox Outbreak

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recommendations! Published in 2022 at "Viruses"

DOI: 10.3390/v14091870

Abstract: Monkeypox disease (MPX) is currently considered a global threat after COVID-19. European Medicines Agency (EMA) approved Tecovirimat in capsule dosage form (200 mg) as the first treatment for MPX in January 2022. This article highlights… read more here.

Keywords: drug; patent literature; development patent; tecovirimat ... See more keywords

MONKEYPOX DISEASE TREATMENT BY TECOVIRIMAT ADSORBED ONTO SINGLE-WALLED CARBON NANOTUBE THROUGH DRUG DELIVERY METHOD

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recommendations! Published in 2023 at "Journal of the Chilean Chemical Society"

DOI: 10.4067/s0717-97072023000105796

Abstract: In this work, it has been investigated the Monkeypox disease which occurs in both humans and animals by infection with a double-stranded DNA virus having the symptoms consisting of fever, fatigue, headache, and muscle pains… read more here.

Keywords: single walled; drug delivery; monkeypox disease; drug ... See more keywords

Tecovirimat Treatment of People With HIV During the 2022 Mpox Outbreak

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recommendations! Published in 2023 at "Annals of Internal Medicine"

DOI: 10.7326/m22-3132

Abstract: BACKGROUND The recent mpox outbreak has disproportionately affected people with HIV (PWH) and resulted in the first widespread use of the novel antiviral tecovirimat. Whether treatment outcomes differ between PWH and those without HIV is… read more here.

Keywords: treated tecovirimat; treatment outcomes; treatment; mpox outbreak ... See more keywords