Cross-Talking of Pathway-Specific Regulators in Glycopeptide Antibiotics (Teicoplanin and A40926) Production
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DOI: 10.3390/antibiotics12040641
Abstract: Teicoplanin and A40926 (natural precursor of dalbavancin) are clinically relevant glycopeptide antibiotics (GPAs) produced by Actinoplanes teichomyceticus NRRL B-16726 and Nonomuraea gerenzanensis ATCC 39727. Their biosynthetic enzymes are coded within large biosynthetic gene clusters (BGCs),… read more here.
Keywords: pathway specific; glycopeptide antibiotics; teicoplanin a40926; gerenzanensis ... See more keywords