The antiviral drug telaprevir induces cell death by reducing FOXA1 expression in estrogen receptor α (ERα)‐positive breast cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13303
Abstract: Previously, we found that telaprevir (Tel), the inhibitor of hepatitis C virus NS3/4A serine protease, reduces estrogen receptor α (ERα) content at the transcriptional level without binding to the receptor, prevents ERα transcriptional activity, and… read more here.
Keywords: cell death; estrogen receptor; breast cancer; induces cell ... See more keywords
Disengagement, engagement and digital skills in technology-enhanced learning
Sign Up to like & getrecommendations! Published in 2019 at "Education and Information Technologies"
DOI: 10.1007/s10639-019-09998-w
Abstract: With the digitalisation of education increasing, the relationship between student engagement in Technology-enhanced Learning (TEL) and digital skills has remained largely unexplored. There is a strong consensus that engagement is necessary for students to succeed… read more here.
Keywords: digital skills; tel; technology enhanced; engagement tel ... See more keywords
In silico prediction coupled with in vitro experiments and absorption modeling to study the inclusion complex of telmisartan with modified beta-cyclodextrin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"
DOI: 10.1007/s10847-018-0797-x
Abstract: Telmisartan (TEL) is a poorly bioavailable antihypertensive drug candidate owing to its low solubility in all the biofluids. The present study is aimed to enhance the solubility of TEL by forming an inclusion complex with… read more here.
Keywords: inclusion; inclusion complex; beta cyclodextrin; tel ... See more keywords
Prevention is better than cure: effects of errors on memory performance during spatial learning in healthy aging
Sign Up to like & getrecommendations! Published in 2020 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-020-01603-2
Abstract: Background Healthy aging is accompanied by a decline in learning ability and memory capacity. One widely-studied method to improve learning outcome is by reducing the occurrence of errors during learning (errorless learning; EL). However, there… read more here.
Keywords: healthy aging; spatial learning; tel; memory performance ... See more keywords
Telmisartan ameliorates dextran sodium sulfate-induced colitis in rats by modulating NF-κB signalling in the context of PPARγ agonistic activity.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.07.014
Abstract: Variations in Nrf-2 and NF-κB expression profiles have been reported in ulcerative colitis (UC), in which an interplay between these two critical pathways has been identified. The therapeutic potential of angiotensin receptor blockers (ARBs) for… read more here.
Keywords: tel; colitis; ppar agonistic; agonistic activity ... See more keywords
Cytotoxic comparison of macrolide antibiotics and their chlorinated disinfection byproduct mixtures.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.109415
Abstract: Erythromycin (ERY), azithromycin (AZI) and telithromycin (TEL) are widely-used macrolide antibiotics that are frequently detected in various water environments, including resource water and drinking water. In the performed chlorination disinfection process, at least 10, 20… read more here.
Keywords: tel; disinfection; azi tel; disinfection byproduct ... See more keywords
Assessment of the greenness of spectrophotometric and micellar liquid chromatographic methods using two approaches: Application to pharmaceutical analysis of hydrochlorothiazide and telmisartan
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.04.058
Abstract: Abstract Recently the focus of analytical community is to eliminate or reduce the usage of hazardous chemicals; consequently, two ecofriendly, rapid, selective and cost-effective methods are developed for the simultaneous determination of hydrochlorothiazide (HCZ) and… read more here.
Keywords: greenness; hydrochlorothiazide; liquid; tel ... See more keywords
(ii) Interim report on the inscriptions from the aedes of the fort near Tel Shalem
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Roman Archaeology"
DOI: 10.1017/s1047759419000126
Abstract: Ever since the discovery of a building inscription of a vexillatio of the legio VI Ferrata near Tel Shalem,1 it was clear that the area was a locus of Roman military activity. In the following… read more here.
Keywords: near tel; tel; tel shalem; fort ... See more keywords
Study on the solubilization of telmisartan by forming cocrystals with aromatic carboxylic acids
Sign Up to like & getrecommendations! Published in 2021 at "CrystEngComm"
DOI: 10.1039/d1ce00551k
Abstract: The solubility of insoluble telmisartan (TEL) was improved by forming new cocrystal forms with several aromatic carboxylic acids. All solid forms showed three dissolution modes: TEL-HBA achieved maximum release equilibrium within 30 min and maintained… read more here.
Keywords: aromatic carboxylic; carboxylic acids; tel; solubilization telmisartan ... See more keywords
Residency Programs in Colon and Rectal Surgery.
Sign Up to like & getrecommendations! Published in 2017 at "Diseases of the colon and rectum"
DOI: 10.1097/01.dcr.0000520862.73572.df
Abstract: NEW YORK State University of New York at Buffalo/ Buffalo General Hospital Amarjit Singh, M.D. 85 High Street Buffalo, NY 14203 Tel: (716) 856-1200 St. Luke's/Roosevelt Hospital Center Thomas H. Dailey, M.D. Department of Surgery… read more here.
Keywords: surgery; tel; colon rectal; rectal surgery ... See more keywords
Telmisartan Exerts Cytotoxicity in Scirrhous Gastric Cancer Cells by Inducing G0/G1 Cell Cycle Arrest
Sign Up to like & getrecommendations! Published in 2021 at "AntiCancer Research"
DOI: 10.21873/anticanres.15358
Abstract: Background/Aim: This study aimed to assess the effects of telmisartan (TEL), a potential antitumor agent, and its mechanism of action in the regulation of apoptosis, autophagy, and cell cycle in scirrhous gastric cancer (SGC). Materials… read more here.
Keywords: scirrhous gastric; tel; gastric cancer; cell cycle ... See more keywords