Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase.
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DOI: 10.1534/genetics.119.302391
Abstract: Mecl/ATR and Tell/ATM trigger replicative senescence when telomeres become critically short in the absence of telomerase, but how Tell/ATM promotes senescence is still unclear. Menin et al. studied the functions of Saccharomyces cerevisiae Tel1 in… read more here.
Keywords: replicative senescence; tel1; absence telomerase; senescence ... See more keywords