Influence of Polymer and Drug Loading on the Release Profile and Membrane Transport of Telaprevir.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00104
Abstract: During the dissolution of amorphous solid dispersions (ASDs), various phase transformations can occur, which will ultimately impact the degree of supersaturation. This study employed dissolution and diffusion measurements to compare the performance of various ASD… read more here.
Keywords: phase; drug; polymer drug; dissolution ... See more keywords
Rapid virological response of telaprevir and boceprevir in a Brazilian cohort of HCV genotype 1 patients: a multicenter longitudinal study
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s124663
Abstract: Background Chronic hepatitis C is a major public health issue, but there is a gap in the literature regarding the effectiveness and safety of direct-acting antiviral agents in the Brazilian population. The main aim of… read more here.
Keywords: virological response; hcv; study; boceprevir ... See more keywords