Telbivudine attenuates UUO‐induced renal fibrosis via TGF‐&bgr;/Smad and NF‐&kgr;B signaling
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DOI: 10.1016/j.intimp.2017.11.043
Abstract: ABSTRACT Renal fibrosis yields decreased renal function and is a potent contributor to chronic kidney disease (CKD). Telbivudine (LdT) is an anti–hepatitis B virus (HBV) drug that has been found to steadily improve renal function,… read more here.
Keywords: bgr smad; fibrosis; kgr; renal fibrosis ... See more keywords
Hepatic flare after telbivudine withdrawal and efficacy of postpartum antiviral therapy for pregnancies with chronic hepatitis B virus
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DOI: 10.1111/jgh.13436
Abstract: The efficacy of telbivudine for breaking vertical transmission of hepatitis B virus has been well established. Data on the risk of postpartum flare after telbivudine withdrawal and efficacy of extended antiviral therapy after delivery are… read more here.
Keywords: flare telbivudine; efficacy; telbivudine withdrawal; withdrawal efficacy ... See more keywords
Safety and efficacy of telbivudine in late pregnancy to prevent mother‐to‐child transmission of hepatitis B virus: A multicenter prospective cohort study
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DOI: 10.1111/jvh.12834
Abstract: Infection of hepatitis B virus (HBV) occurs in ~10% of infants of HBV‐infected mothers with positive hepatitis B e antigen (HBeAg) after immunoprophylaxis. We aimed to evaluate the safety and efficacy of telbivudine used during… read more here.
Keywords: pregnancy; hepatitis; transmission; hbv ... See more keywords
Telbivudine versus entecavir in patients with undetectable hepatitis B virus DNA: a randomized trial
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DOI: 10.1186/s12876-017-0572-2
Abstract: BackgroundTelbivudine has been suggested to induce hepatitis B surface antigen (HBsAg) decline to the similar degree as pegylated interferon. We aimed to investigate whether telbivudine could further decrease HBsAg titer in patients who maintain undetectable… read more here.
Keywords: entecavir; trial; dna; hepatitis ... See more keywords