Mechanistic Investigations Support Liver Safety of Ubrogepant
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DOI: 10.1093/toxsci/kfaa093
Abstract: Abstract Small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated therapeutic efficacy for the treatment of migraine. However, previously investigated CGRP receptor antagonists, telcagepant and MK-3207, were discontinued during clinical development because of concerns about… read more here.
Keywords: cgrp receptor; telcagepant 3207; support liver; mechanistic investigations ... See more keywords