Articles with "telomerase holoenzyme" as a keyword



Overexpression of the telomerase holoenzyme induces EMT and tumorigenesis of HPV‐immortalized keratinocytes

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Published in 2023 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28681

Abstract: Cervical cancer is the most frequent malignancy of the female genital tract and is associated with persistent infection of the uterine cervix with high‐risk human papillomaviruses (HPV). The two HPV oncoproteins, E6 and E7, cooperatively… read more here.

Keywords: overexpression telomerase; telomerase; immortalized keratinocytes; hpv ... See more keywords
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Single-Run Catalysis and Kinetic Control of Human Telomerase Holoenzyme.

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Published in 2021 at "Advances in experimental medicine and biology"

DOI: 10.1007/5584_2021_676

Abstract: Genome stability in eukaryotic cells relies on proper maintenance of telomeres at the termini of linear chromosomes. Human telomerase holoenzyme is required for maintaining telomere stability in a majority of proliferative human cells, making it… read more here.

Keywords: telomerase holoenzyme; control human; human telomerase; telomerase ... See more keywords
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A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme

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Published in 2020 at "Microbial Cell"

DOI: 10.15698/mic2020.09.730

Abstract: RNase P, an RNA-protein complex, is essential for processing tRNAs. Three of the ten protein subunits of Saccharomyces cerevisiae RNase P (and a related complex, RNase MRP) co-purify with yeast telomerase, another RNA-protein complex. The… read more here.

Keywords: telomerase; rnase; rna; pop ... See more keywords