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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01343
Abstract: Telomerase is essential for the immortality characteristics of most cancers. Telomerase-specific inhibitors should render cancer cells to replicative senescence without acute cytotoxicity. Perylene-based G-quadruplex (G4) ligands are widely studied as telomerase inhibitors. Most reported perylene-based…
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Keywords:
telomerase;
cytotoxicity;
perylene monoimide;
telomerase inhibitors ... See more keywords
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Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19010013
Abstract: Telomeres and telomerase are nowadays exploring traits on targets for anticancer therapy. Telomerase is a unique reverse transcriptase enzyme, considered as a primary factor in almost all cancer cells, which is mainly responsible to regulate…
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Keywords:
telomerase;
natural products;
telomerase inhibitors;
inhibitors natural ... See more keywords