TPP1 OB-fold domain protein suppresses cell proliferation and induces cell apoptosis by inhibiting telomerase recruitment to telomeres in human lung cancer cells
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DOI: 10.1007/s00432-019-02921-3
Abstract: PurposeMaintaining telomeres by recruiting telomerase-to-chromosome ends is essential for cancer cell survival. Inhibiting telomerase recruitment to telomeres represents a novel strategy for telomere-based lung cancer therapy. However, approaches for interrupting telomerase recruitment for cancer therapy… read more here.
Keywords: telomerase recruitment; tpp1; lung cancer; cancer cells ... See more keywords