A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2023 at "Genetics"
DOI: 10.1093/genetics/iyad076
Abstract: Telomere healing occurs when telomerase, normally restricted to chromosome ends, acts upon a double-strand break to create a new, functional telomere. De novo telomere addition on the centromere-proximal side of a break truncates the chromosome… read more here.
Keywords: hotspots novo; addition; comprehensive map; telomere addition ... See more keywords
Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz1109
Abstract: Abstract The healing of broken chromosomes by de novo telomere addition, while a normal developmental process in some organisms, has the potential to cause extensive loss of heterozygosity, genetic disease, or cell death. However, it… read more here.
Keywords: telomere addition; dna double; dnta; double strand ... See more keywords