Altered expression of telomere‐associated genes in leukocytes among BRCA1 and BRCA2 carriers
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22773
Abstract: Telomere dysfunction resulting from telomere shortening and deregulation of shelterin components has been linked to the pathogenesis of age‐related disorders, including cancer. Recent evidence suggests that BRCA1/2 (BRCA1 and BRCA2) tumor suppressor gene products play… read more here.
Keywords: brca1 brca2; brca1 carriers; expression telomere; telomere associated ... See more keywords
The knockdown efficiency of telomere associated genes with specific methodology in a zebrafish cell line.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.06.013
Abstract: Zebrafish is broadly used as a model organism in gene loss-of-function studies in vivo, but its employment in vitro is greatly limited by the lack of efficient gene knockdown approaches in zebrafish cell lines such… read more here.
Keywords: methodology; telomere associated; gene; zebrafish cell ... See more keywords