Physician-Training Stress and Accelerated Cellular Aging
Sign Up to like & getrecommendations! Published in 2019 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2019.04.030
Abstract: BACKGROUND Stress is a key precipitant for many common diseases, but established biological markers to track stress and guide investigations into mechanisms linking stress and disease are lacking. Cross-sectional studies have identified correlations between stress… read more here.
Keywords: physician training; year; attrition; stress ... See more keywords
Cardiac telomere attrition following changes in the expression of shelterin genes in pulmonary hypertensive chickens.
Sign Up to like & getrecommendations! Published in 2023 at "British poultry science"
DOI: 10.1080/00071668.2022.2163877
Abstract: ABSTRACT 1. The alterations of relative telomere length and expression of shelterin genes (TRF1, TRF2, RAP1, POT1, and TPP1) were evaluated from the chickens’ right heart ventricle in the early and last stages of cold-induced… read more here.
Keywords: shelterin genes; expression shelterin; group; telomere attrition ... See more keywords
Controlling for baseline telomere length biases estimates of the rate of telomere attrition
Sign Up to like & getrecommendations! Published in 2019 at "Royal Society Open Science"
DOI: 10.1098/rsos.190937
Abstract: Longitudinal studies have sought to establish whether environmental exposures such as smoking accelerate the attrition of individuals' telomeres over time. These studies typically control for baseline telomere length (TL) by including it as a covariate… read more here.
Keywords: baseline telomere; telomere length; controlling baseline; attrition ... See more keywords
Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions
Sign Up to like & getrecommendations! Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13357
Abstract: Telomere attrition has been proposed as a biomarker and causal factor in aging. In addition to causing cellular senescence and apoptosis, telomere shortening has been found to affect gene expression in subtelomeric regions. Here, we… read more here.
Keywords: telomere attrition; gene; gene expression; age related ... See more keywords
A genetic determinant of VEGF-A levels is associated with telomere attrition.
Sign Up to like & getrecommendations! Published in 2021 at "Aging"
DOI: 10.18632/aging.203636
Abstract: Telomere length (TL) is a hallmark of cellular aging and is associated with chronic diseases development. The vascular endothelial growth factor A (VEGF-A), a potent angiogenesis factor, is implicated in the pathophysiology of many chronic… read more here.
Keywords: chronic diseases; vegf; telomere attrition; determinant vegf ... See more keywords
Low Magnesium in Conjunction with High Homocysteine and Less Sleep Accelerates Telomere Attrition in Healthy Elderly Australian
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24020982
Abstract: The relationship between sleep and micronutrients, including magnesium, is implicated in its regulation. The effects of low magnesium and other micronutrients on sleep disruption and telomere loss are not well understood. The present study was… read more here.
Keywords: magnesium; homocysteine; healthy elderly; low magnesium ... See more keywords