Association of Telomere Length With Risk of Disease and Mortality.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2021.7804
Abstract: Importance Telomeres protect DNA from damage. Because they shorten with each mitotic cycle, leukocyte telomere length (LTL) serves as a mitotic clock. Reduced LTL has been associated with multiple human disorders. Objective To determine the… read more here.
Keywords: ltl associated; telomere length; mortality; risk ... See more keywords
Association of Leukocyte Telomere Length With Mortality Among Adult Participants in 3 Longitudinal Studies
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.0023
Abstract: Key Points Question Is leukocyte telomere length associated with the natural life span of contemporary humans? Findings This cohort study included 3259 participants from 3 longitudinal studies, of whom 1525 died during the follow-up period.… read more here.
Keywords: longitudinal studies; leukocyte telomere; telomere length; mortality ... See more keywords
Prenatal Air Pollution and Newborns' Predisposition to Accelerated Biological Aging
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.3024
Abstract: Importance Telomere length is a marker of biological aging that may provide a cellular memory of exposures to oxidative stress and inflammation. Telomere length at birth has been related to life expectancy. An association between… read more here.
Keywords: cord blood; telomere length; birth; exposure ... See more keywords
Sociodemographic correlates and family aggregation of leukocyte telomere length in adults and children from Mesoamerica
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.22942
Abstract: Telomere length is a biomarker of cumulative stress and inflammation related to chronic disease risk. We examined the associations of leukocyte telomere length (LTL) with sociodemographic and anthropometric variables and estimated LTL family aggregation in… read more here.
Keywords: leukocyte telomere; telomere length; family aggregation;
The relation between sensory processing sensitivity and telomere length in adolescents
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2751
Abstract: In the present study, we investigated the association between sensory processing sensitivity (SPS) and telomere length (TL), which is considered a biomarker of cellular aging. SPS is an individual characteristic describing increased perception and procession… read more here.
Keywords: telomere length; sensory processing; processing sensitivity;
Shorter telomere length increases age‐related tumor risks in von Hippel‐Lindau disease patients
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1134
Abstract: Von Hippel‐Lindau (VHL) disease is a rare autosomal dominant cancer syndrome caused by alterations of VHL gene. Patients are predisposed to develop pheochromocytomas and solid or cystic tumors of the central nervous system, kidney, pancreas,… read more here.
Keywords: age related; age; telomere length; related tumor ... See more keywords
Reliable blood cancer cells' telomere length evaluation by qPCR
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2816
Abstract: Telomere shortening is linked to a range of different human diseases, hence reliable measurement methods are needed to uncover such associations. Among the plethora of telomere length measurement methods, qPCR is reported as easy to… read more here.
Keywords: blood cancer; telomere length; cells telomere; reliable blood ... See more keywords
MicroRNA‐340‐5p increases telomere length by targeting telomere protein POT1 to improve Alzheimer's disease in mice
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11576
Abstract: Alzheimer′s disease (AD) is a chronic neurodegenerative disorder which is the primary cause of dementia in the elderly. Telomere attrition has been proposed as a hallmark of aging. Our study aimed to explore the mechanism… read more here.
Keywords: alzheimer disease; telomere length; pot1 expression; microrna 340 ... See more keywords
The relation of telomere length at midlife to subsequent 20‐year depression trajectories among women
Sign Up to like & getrecommendations! Published in 2019 at "Depression and Anxiety"
DOI: 10.1002/da.22892
Abstract: Telomeres cap and protect DNA but shorten with each somatic cell division. Aging and environmental and lifestyle factors contribute to the speed of telomere attrition. Current evidence suggests a link between relative telomere length (RTL)… read more here.
Keywords: depression; telomere length; length midlife; midlife subsequent ... See more keywords
Telomere length as a predictor of emotional processing in the brain
Sign Up to like & getrecommendations! Published in 2019 at "Human Brain Mapping"
DOI: 10.1002/hbm.24487
Abstract: Shorter telomere length (TL) has been associated with the development of mood disorders as well as abnormalities in brain morphology. However, so far, no studies have considered the role TL may have on brain function… read more here.
Keywords: telomere length; activation; brain; length predictor ... See more keywords
Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31251
Abstract: Telomeres are crucial in the maintenance of chromosome integrity and genomic stability. Critically short telomeres can trigger programed cell death while cells with longer telomeres may have increased likelihood of replicative errors, resulting in genetic… read more here.
Keywords: lung adenocarcinoma; telomere length; study; chinese health ... See more keywords