Absorption of Low-Energy UV Radiation by Human Telomere G-Quadruplexes Generates Long-Lived Guanine Radical Cations.
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DOI: 10.1021/jacs.7b05931
Abstract: Telomeres, which are involved in cell division, carcinogenesis, and aging and constitute important therapeutic targets, are prone to oxidative damage. This propensity has been correlated with the presence of guanine-rich sequences, capable of forming four-stranded… read more here.
Keywords: absorption; telomere quadruplexes; human telomere; radical cations ... See more keywords