Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination
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DOI: 10.1093/nar/gkad236
Abstract: Abstract The long non-coding telomeric RNA transcript TERRA, in the form of an RNA–DNA duplex, regulates telomere recombination. In a screen for nucleases that affects telomere recombination, mutations in DNA2, EXO1, MRE11 and SAE2 cause… read more here.
Keywords: loop; dna; recombination; flap endonuclease ... See more keywords