Dexmedetomidine attenuates hypoxia‐induced cardiomyocyte injury by promoting telomere/telomerase activity: Possible involvement of ERK1/2‐Nrf2 signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11799
Abstract: Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, possesses cardioprotection against ischemic/hypoxic injury, but the exact mechanism is not fully elucidated. Since telomere/telomerase dysfunction is involved in myocardial ischemic damage, the present study aimed to investigate… read more here.
Keywords: signaling pathway; nrf2 signaling; dex; erk1 nrf2 ... See more keywords
Interventions Addressing the Telomere-Telomerase System.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-32-9721-0_26
Abstract: Major psychiatric disorders are linked to early mortality and patients afflicted with these ailments demonstrate an increased risk of developing physical diseases that are characteristically seen in the elderly. Psychiatric conditions like major depressive disorder,… read more here.
Keywords: telomere telomerase; telomerase; psychiatric illnesses; telomerase system ... See more keywords
The Relationship Between Vitamin D and Telomere/Telomerase: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2020 at "The Journal of Frailty & Aging"
DOI: 10.14283/jfa.2020.33
Abstract: Telomeres are repetitive nucleotide sequences that together with the associated sheltrin complex protect the ends of chromosomes and maintain genomic stability. Evidences from various organisms suggests that several factors influence telomere length regulation, such as… read more here.
Keywords: telomere telomerase; vitamin telomere; biology; vitamin ... See more keywords