Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies
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DOI: 10.3389/fonc.2019.01518
Abstract: Achieving replicative immortality is a crucial step in tumorigenesis and requires both bypassing cell cycle checkpoints and the extension of telomeres, sequences that protect the distal ends of chromosomes during replication. In the majority of… read more here.
Keywords: alternative lengthening; telomeres pediatric; mechanisms therapies; pediatric cancer ... See more keywords