A practical qPCR approach to detect TERRA, the elusive telomeric repeat-containing RNA.
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DOI: 10.1016/j.ymeth.2016.08.004
Abstract: Telomeres, the heterochromatic structures that protect the ends of the chromosomes, are transcribed into a class of long non-coding RNAs, telomeric repeat-containing RNAs (TERRA), whose transcriptional regulation and functions are not well understood. The identification… read more here.
Keywords: chromosome ends; repeat containing; practical qpcr; telomeric repeat ... See more keywords
Telomeric repeat‐containing RNA (TERRA) related to polycystic ovary syndrome (PCOS)
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DOI: 10.1111/cen.13283
Abstract: Telomeric repeat‐containing RNA (TERRA) participates in the regulation of telomere length, and leucocyte telomere length (LTL) plays an important role in the pathophysiology of polycystic ovary syndrome (PCOS), but little is known about the role… read more here.
Keywords: polycystic ovary; repeat containing; containing rna; ovary syndrome ... See more keywords
PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells.
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DOI: 10.1261/rna.076281.120
Abstract: Telomeric repeat-containing RNA (TERRA) molecules play important roles at telomeres, from heterochromatin regulation to telomerase activity control. In human cells, TERRA is transcribed from subtelomeric promoters located on most chromosome ends and associates with telomeres.… read more here.
Keywords: par terra; repeat containing; containing rna; telomeric repeat ... See more keywords