Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response
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DOI: 10.1038/s41598-017-02905-8
Abstract: Circulating cell-free DNA (cfDNA) may be involved in immune response regulation. We studied the variations in abundance of telomeric sequences in plasma and serum in young healthy volunteers and the ability of cfDNA contained in… read more here.
Keywords: cell free; serum; telomeric sequences; immune response ... See more keywords
Interrogating accessibility of telomeric sequences with FRET-PAINT: evidence for length-dependent telomere compaction
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DOI: 10.1093/nar/gkab067
Abstract: Abstract Single-stranded telomeric overhangs are ∼200 nucleotides long and can form tandem G-quadruplex (GQ) structures, which reduce their accessibility to nucleases and proteins that activate DNA damage response. Whether these tandem GQs further stack to… read more here.
Keywords: interrogating accessibility; accessibility; fret paint; telomeric sequences ... See more keywords
Distribution of Interstitial Telomeric Sequences in Primates and the Pygmy Tree Shrew (Scandentia)
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DOI: 10.1159/000467634
Abstract: It has been hypothesized that interstitial telomeric sequences (ITSs), i.e., repeated telomeric DNA sequences found at intrachromosomal sites in many vertebrates, could be correlated to chromosomal rearrangements and plasticity. To test this hypothesis, we hybridized… read more here.
Keywords: interstitial telomeric; primates pygmy; distribution interstitial; sequences primates ... See more keywords
Prenatal Diagnosis of Trisomy 2p due to Terminal 2p Duplication including Interstitial Telomeric Sequences
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DOI: 10.1159/000485392
Abstract: We report on a prenatally diagnosed unusual case of inverted terminal duplication of the short arm of chromosome 2, leading to interstitial telomeric sequences (ITSs) and partial trisomy 2p. To our knowledge, there are only… read more here.
Keywords: trisomy; duplication; terminal duplication; interstitial telomeric ... See more keywords