Long non-coding RNA in glioma: novel genetic players in temozolomide resistance
Sign Up to like & getrecommendations! Published in 2023 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2023.2175497
Abstract: ABSTRACT Glioma is the most common primary malignant brain tumor in adults and accounts for approximately 80% of brain and central nervous system tumors. In 2021, the World Health Organization (WHO) published a new taxonomy… read more here.
Keywords: long non; temozolomide resistance; glioma; coding rna ... See more keywords
XPA Enhances Temozolomide Resistance of Glioblastoma Cells by Promoting Nucleotide Excision Repair
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221092778
Abstract: Glioblastoma is the most frequent, as well as aggressive kind of high-grade malignant glioma. Chemoresistance is posing a significant clinical barrier to the efficacy of temozolomide-based glioblastoma treatment. By suppressing xeroderma pigmentosum group A (XPA),… read more here.
Keywords: glioblastoma; xpa; nucleotide excision; temozolomide resistance ... See more keywords
Identification and verification of the temozolomide resistance feature gene DACH1 in gliomas
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1120103
Abstract: Introduction The most important chemotherapy treatment for glioma patients is temozolomide. However, the development of drug resistance severely restricts the use of temozolomide. Therefore, elucidating the mechanism of temozolomide resistance, enhancing temozolomide sensitivity, and extending… read more here.
Keywords: temozolomide resistance; resistance; dach1; gene dach1 ... See more keywords
An overview of glioblastoma multiforme and temozolomide resistance: can LC-MS-based proteomics reveal the fundamental mechanism of temozolomide resistance?
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1166207
Abstract: Glioblastoma multiforme (GBM) is a primary type of lethal brain tumor. Over the last two decades, temozolomide (TMZ) has remained the primary chemotherapy for GBM. However, TMZ resistance in GBM constitutes an underlying factor contributing… read more here.
Keywords: temozolomide resistance; resistance; based proteomics; glioblastoma multiforme ... See more keywords