Activity-based probes for the high temperature requirement A serine proteases.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical biology"
DOI: 10.1021/acschembio.0c00279
Abstract: The high temperature requirement A (HTRA) family of serine proteases mediates protein quality control. These proteins process misfolded proteins in several diseases including Alzheimer's disease (AD) and Parkinson's disease (PD). While their structures and activation… read more here.
Keywords: serine proteases; based probes; high temperature; activity based ... See more keywords
E-Cadherin Orthologues as Substrates for the Serine Protease High Temperature Requirement A (HtrA)
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12030356
Abstract: Helicobacter pylori (H. pylori) expresses the serine protease and chaperone High temperature requirement A (HtrA) that is involved in periplasmic unfolded protein stress response. Additionally, H. pylori-secreted HtrA directly cleaves the human cell adhesion molecule… read more here.
Keywords: temperature requirement; cadherin orthologues; serine protease; htra ... See more keywords