Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag.
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DOI: 10.1021/acs.bioconjchem.8b00284
Abstract: The high specificity and favorable pharmacological properties of monoclonal antibodies (mAbs) have prompted significant interest in re-engineering this class of molecules to add novel functionalities for enhanced therapeutic and diagnostic potential. Here, we used the… read more here.
Keywords: natural amino; monoclonal antibodies; template; chemistry ... See more keywords