RNA Polymerase Ribozyme That Recognizes the Template-Primer Complex through Tertiary Interactions.
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DOI: 10.1021/acs.biochem.3c00091
Abstract: RNA enzymes (ribozymes) often rely on specific base-pairing interactions to engage RNA substrates, which limits the substrate sequence generality of these enzymes. An RNA polymerase ribozyme that was previously optimized by directed evolution to operate… read more here.
Keywords: polymerase ribozyme; polymerase; template primer; ribozyme ... See more keywords