Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Toxicology"
DOI: 10.1007/s00204-018-2256-2
Abstract: The utilisation of genome-wide transcriptomics has played a pivotal role in advancing the field of toxicology, allowing the mapping of transcriptional signatures to chemical exposures. These activities have uncovered several transcriptionally regulated pathways that can… read more here.
Keywords: tempo seq; chemical induced; rptec tert1; induced transcriptomic ... See more keywords
Abstract 2106: Focal gene expression profiling of counterstained FFPE with correlation to morphology using TempO-Seq
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-2106
Abstract: We previously reported on use of the whole transcriptome TempO-Seq® assay to profile gene expression from 1 mm2 focal areas of 5 µm thick FFPE sections of normal and cancerous tissue to identify disease biomarkers… read more here.
Keywords: gene expression; morphology; gene; tempo seq ... See more keywords
A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0178302
Abstract: The use of gene expression signatures to classify compounds, identify efficacy or toxicity, and differentiate close analogs relies on the sensitivity of the method to identify modulated genes. We used a novel ligation-based targeted whole… read more here.
Keywords: whole transcriptome; tempo seq; expression; signature ... See more keywords