Spatio-temporal control of targeted gene expression in combination with CRISPR/Cas and Tet-On systems in Medaka.
Sign Up to like & getrecommendations! Published in 2023 at "Genesis"
DOI: 10.1002/dvg.23519
Abstract: Spatial and temporal control of transgene expression is a powerful approach to understand gene functions in specific cells and tissues. The Tet-On system is a robust tool for controlling transgene expression spatially and temporally; however,… read more here.
Keywords: system; expression; gene expression; gene ... See more keywords
Striatal dopamine and the temporal control of behavior
Sign Up to like & getrecommendations! Published in 2019 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.08.030
Abstract: Striatal dopamine strongly regulates how individuals use time to guide behavior. Dopamine acts on D1- and D2- dopamine receptors in the striatum. However, the relative role of these receptors in the temporal control of behavior… read more here.
Keywords: control; dopamine temporal; temporal control; striatal dopamine ... See more keywords
Stimulating Cerebellar Outflow Reveals Temporal Control of Motor Cortical Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.05.044
Abstract: Nashef et al. (2019) show that high-frequency stimulation of the superior cerebellar peduncle produces a temporary cerebellar deficit. While the deficit is present, motor cortex neurons that receive cerebellar input maintain their directional tuning but lose… read more here.
Keywords: outflow reveals; cerebellar outflow; stimulating cerebellar; temporal control ... See more keywords
Sensory attenuation is modulated by the contrasting effects of predictability and control
Sign Up to like & getrecommendations! Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.118103
Abstract: Self-generated stimuli have been found to elicit a reduced sensory response compared with externally-generated stimuli. However, much of the literature has not adequately controlled for differences in temporal predictability and temporal control of the stimuli.… read more here.
Keywords: temporal control; control; sensory attenuation; temporal predictability ... See more keywords
Reversible, Spatial and Temporal Control over Protein Activity Using Light.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2018.05.004
Abstract: In biomedical sciences, the function of a protein of interest is investigated by altering its net activity and assessing the consequences for the cell or organism. To change the activity of a protein, a wide… read more here.
Keywords: protein; control; spatial temporal; temporal control ... See more keywords
Autonomous Temporal Control of Hydrogen Sulfide Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04534
Abstract: Hydrogen sulfide (H2S) is dichotomous in nature as it is lethal at higher concentrations, but at lower concentrations it shows a more cytoprotective nature. Due to its involvement in many physiological processes, it has recently… read more here.
Keywords: control; autonomous temporal; temporal control; control hydrogen ... See more keywords
Precise spatio-temporal control of rapid optogenetic cell ablation with mem-KillerRed in Zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05028-2
Abstract: The ability to kill individual or groups of cells in vivo is important for studying cellular processes and their physiological function. Cell-specific genetically encoded photosensitizing proteins, such as KillerRed, permit spatiotemporal optogenetic ablation with low-power… read more here.
Keywords: ablation; spatio temporal; temporal control; control rapid ... See more keywords
Temporal control of RAFT polymerization via magnetic catalysis
Sign Up to like & getrecommendations! Published in 2020 at "Polymer Chemistry"
DOI: 10.1039/d0py00220h
Abstract: Magnetic core–shell structured catalysts, Fe3O4@Fe(II)–MOF nanoparticles (NPs), are synthesized in two steps including solvothermal synthesis of Fe3O4 NPs and self-assembly of Fe(II)–MOF particles on the core. They successfully enabled the real time and temporal control… read more here.
Keywords: magnetic catalysis; temporal control; raft polymerization; polymerization ... See more keywords
Temporal control of the integrated stress response by a stochastic molecular switch
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abk2022
Abstract: Stress granules (SGs) are formed in the cytosol as an acute response to environmental cues and activation of the integrated stress response (ISR), a central signaling pathway controlling protein synthesis. Using chronic virus infection as… read more here.
Keywords: stress response; response; temporal control; integrated stress ... See more keywords
Monolithic 3D phase profile formation in glass for spatial and temporal control of optical waves.
Sign Up to like & getrecommendations! Published in 2022 at "Optics express"
DOI: 10.1364/oe.460538
Abstract: Optical manufacturing technologies play a central role in modern science and engineering. Progress on both subtractive and additive fabrications is transforming the implementation of optical technologies. Despite the recent advances, modern fabrication still faces challenges… read more here.
Keywords: profile formation; phase profile; monolithic phase; formation glass ... See more keywords
p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1006828
Abstract: Cleft palate is a common congenital disorder that affects up to 1 in 2500 live births and results in considerable morbidity to affected individuals and their families. The aetiology of cleft palate is complex with… read more here.
Keywords: cleft palate; spatio temporal; control palatal; temporal control ... See more keywords