Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex
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DOI: 10.1093/cercor/bhv346
Abstract: Abstract Focal cortical dysplasias (FCDs) are local malformations of the human neocortex with strong epileptogenic potential. To investigate the underlying pathomechanisms, we performed a whole human transcriptome screening to compare the gene expression pattern of… read more here.
Keywords: whole transcriptome; myelin; temporal neocortex; screening reveals ... See more keywords
Expression of Aquaporin 1 and Aquaporin 4 in the Temporal Neocortex of Patients with Parkinson's Disease
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DOI: 10.1111/bpa.12369
Abstract: The astrocytic water channel proteins aquaporin 1 (AQP1) and aquaporin 4 (AQP4) are known to be altered in brains affected by several neurodegenerative disorders, including Alzheimer's disease. However, AQP expression in brains affected by Parkinson's… read more here.
Keywords: neocortex patients; expression; temporal neocortex; parkinson disease ... See more keywords
Increased florbetapir binding in the temporal neocortex from age 20 to 60 years
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DOI: 10.1212/wnl.0000000000004733
Abstract: Objective: To improve our understanding of early β-amyloid (Aβ) accumulation processes using florbetapir-PET scan in 20- to 60-year-old individuals. Methods: Seventy-six cognitively normal individuals aged 20 to 60 years, 57 cognitively normal older individuals (61–84… read more here.
Keywords: accumulation; years old; age; florbetapir binding ... See more keywords