Population pharmacokinetics of temsirolimus and sirolimus in children with recurrent solid tumours: a report from the Children's Oncology Group
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DOI: 10.1111/bcp.13181
Abstract: Aims Temsirolimus is an inhibitor of the mammalian target of rapamycin (mTOR). Pharmacokinetic (PK) characterization of temsirolimus in children is limited and there is no paediatric temsirolimus population PK model available. The objective of this… read more here.
Keywords: temsirolimus sirolimus; model; oncology; population ... See more keywords