Bringing tendon biology to heel: Leveraging mechanisms of tendon development, healing, and regeneration to advance therapeutic strategies
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Dynamics"
DOI: 10.1002/dvdy.269
Abstract: Tendons are specialized matrix‐rich connective tissues that transmit forces from muscle to bone and are essential for movement. As tissues that frequently transfer large mechanical loads, tendons are commonly injured in patients of all ages.… read more here.
Keywords: tendon development; development healing; tendon biology; tendon ... See more keywords
mTORC1 Signaling is a Critical Regulator of Postnatal Tendon Development
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17384-0
Abstract: Tendons transmit contractile forces between musculoskeletal tissues. Whereas the biomechanical properties of tendons have been studied extensively, the molecular mechanisms regulating postnatal tendon development are not well understood. Here we examine the role of mTORC1… read more here.
Keywords: tendon; tendon development; mtorc1 signaling; postnatal tendon ... See more keywords
Comparison of Tendon Development Versus Tendon Healing and Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.821667
Abstract: Tendon is a vital connective tissue in human skeletal muscle system, and tendon injury is very common and intractable in clinic. Tendon development and repair are two closely related but still not fully understood processes.… read more here.
Keywords: tendon development; comparison tendon; tendon; process ... See more keywords