A data-driven approach finds RNA polymerase III antibody and tendon friction rubs as enrichment tools for early diffuse scleroderma trials.
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DOI: 10.1093/rheumatology/keac501
Abstract: OBJECTIVE Clinical trials in early diffuse systemic sclerosis (SSc) have consistently shown a placebo group response with a declining modified Rodnan skin score (mRSS), with negative outcomes. Our objective was to identify strategies using clinical… read more here.
Keywords: friction rubs; rna polymerase; enrichment; tendon friction ... See more keywords