Energy‐Supporting Enzyme‐Mimic Nanoscaffold Facilitates Tendon Regeneration Based on a Mitochondrial Protection and Microenvironment Remodeling Strategy (Adv. Sci. 31/2022)
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202542
Abstract: Tendon injury is a tricky and prevalent motor system disease, leading to compromised daily activity and disability. Insufficient regenerative capability and dysregulation of immune microenvironment are the leading causes of functional loss. First, this work… read more here.
Keywords: regeneration; tendon regeneration; microenvironment; nbs ceo ... See more keywords
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose‐Derived Stem Cells
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202417447
Abstract: Tendons are vital for maintaining integrity and movement, but current treatment options are insufficient for their regeneration after injuries. Previous studies have shown that the secretome from mesenchymal stem cells (MSCs) promoted tendon regeneration. However,… read more here.
Keywords: topography; stem cells; adipose derived; tendon regeneration ... See more keywords
A Natural Hydrogel with Prohealing Properties Enhances Tendon Regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202105255
Abstract: Tendon regeneration and reduction of peritendinous adhesion remain major clinical challenges. This study addresses these challenges by adopting a unique hydrogel derived from the skin secretion of Andrias davidianus (SSAD) and taking advantage of its… read more here.
Keywords: ssad derived; tendon regeneration; derived hydrogel; hydrogel ... See more keywords
Knee flexion strength deficits correlate with distal extent of tendon regeneration after hamstring harvest. Preliminary data from an Ultrasound based classification.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical orthopaedics and trauma"
DOI: 10.1016/j.jcot.2020.05.024
Abstract: Background As more evidence comes to light that hamstring harvesting may not be as benign a procedure as previously thought, considerable interest is being generated towards corelating the knee flexural strength deficits with the degree… read more here.
Keywords: strength deficits; strength; flexion strength; regeneration ... See more keywords
In-vitro and in-vivo assessment of biocompatibility and efficacy of ostrich eggshell membrane combined with platelet-rich plasma in Achilles tendon regeneration
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-85131-x
Abstract: Tendon injuries present significant medical, social, and economic challenges globally. Despite advancements in tendon injury repair techniques, outcomes remain suboptimal due to inferior tissue quality and functionality. Tissue engineering offers a promising avenue for tendon… read more here.
Keywords: esm prp; prp; tendon regeneration; biocompatibility ... See more keywords
Structural characterization of newt tendon regeneration after complete transection: In vivo two-photon imaging and transmission electron microscopy.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of anatomy"
DOI: 10.1111/joa.70036
Abstract: Mammalian tendons, including human tendons, possess limited regeneration capability, and its healing results in scar tissue formation. However, it was recently shown that tendons of newts, amphibians that exhibit regeneration capacity in various tissues and… read more here.
Keywords: transection; newt tendon; complete transection; tendon regeneration ... See more keywords
Molecular Mechanisms of Fetal Tendon Regeneration Versus Adult Fibrous Repair
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22115619
Abstract: Tendinopathies are painful, disabling conditions that afflict 25% of the adult human population. Filling an unmet need for realistic large-animal models, we here present an ovine model of tendon injury for the comparative study of… read more here.
Keywords: adult; fetal tendon; regeneration; tendon regeneration ... See more keywords
Decellularized Extracellular Matrix-Based Bioinks for Tendon Regeneration in Three-Dimensional Bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232112930
Abstract: In the last few years, attempts to improve the regeneration of damaged tendons have been rising due to the growing demand. However, current treatments to restore the original performance of the tissue focus on the… read more here.
Keywords: based bioinks; regeneration; extracellular matrix; tendon regeneration ... See more keywords
Various Strategies of Tendon Stem/Progenitor Cell Reprogramming for Tendon Regeneration
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252111745
Abstract: Rotator cuff tears (RCT) are the most common cause of shoulder pain among adults. “Rotator cuff” refers to the four muscles that cover the shoulder joint: supraspinatus, infraspinatus, subscapularis, and teres minor. These muscles help… read more here.
Keywords: various strategies; tendon regeneration; stem progenitor; tendon stem ... See more keywords