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Published in 2019 at "Nature cell biology"
DOI: 10.1038/s41556-019-0417-z
Abstract: Tendon injuries cause prolonged disability and never recover completely. Current mechanistic understanding of tendon regeneration is limited. Here, we use single-cell transcriptomics to identify a tubulin polymerization-promoting protein family member 3-expressing (Tppp3+) cell population as…
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Keywords:
cell;
regeneration;
tendon stem;
tppp3 pdgfra ... See more keywords
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Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm01287h
Abstract: Poor tendon repair remains a clinical problem due to the difficulties in replicating the complex multiscale hierarchical structure of native tendons. In this work, a bioinspired fibrous scaffold with bimodal micro-nanofibers and a teno-inductive aligned…
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Keywords:
bimodal micro;
progenitor cells;
stem progenitor;
micro nanofibrous ... See more keywords
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3945195
Abstract: Tendon stem cells (TSCs) are often exposed to oxidative stress at tendon injury sites, which impairs their physiological effect as well as therapeutic application. Recently, extracellular vesicles (EVs) derived from bone marrow mesenchymal stem cells…
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Keywords:
tendon stem;
bmsc evs;
eug bmsc;
stem ... See more keywords
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Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.960694
Abstract: Hierarchical anisotropy structure directing 3D cellular orientation plays a crucial role in designing tendon tissue engineering scaffolds. Despite recent development of fabrication technologies for controlling cellular organization and design of scaffolds that mimic the anisotropic…
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Keywords:
structure;
tendon tissue;
tenogenic differentiation;
stem progenitor ... See more keywords
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Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.654084
Abstract: Tendon repair is a medical challenge. Our present study investigated the effectiveness of acellular therapy consisting of conditioned medium (CM) of tendon stem cells (TSCs) induced with hepatocyte growth factor (HGF) in promoting the healing…
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Keywords:
conditioned medium;
injured achilles;
tendon stem;
achilles tendon ... See more keywords