Symptomatic Intracranial Hemorrhage With Tenecteplase vs Alteplase in Patients With Acute Ischemic Stroke: The Comparative Effectiveness of Routine Tenecteplase vs Alteplase in Acute Ischemic Stroke (CERTAIN) Collaboration.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.1449
Abstract: Importance Symptomatic intracranial hemorrhage (sICH) is a serious complication of stroke thrombolytic therapy. Many stroke centers have adopted 0.25-mg/kg tenecteplase instead of alteplase for stroke thrombolysis based on evidence from randomized comparisons to alteplase as… read more here.
Keywords: tenecteplase; acute ischemic; tenecteplase alteplase; stroke ... See more keywords
Different doses of tenecteplase vs alteplase in thrombolysis therapy of acute ischemic stroke: evidence from randomized controlled trials
Sign Up to like & getrecommendations! Published in 2018 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s170803
Abstract: Background Recent studies showed inconsistent results of tenecteplase vs alteplase for acute ischemic stroke (AIS) with safety and efficacy. Methods A meta-analysis was performed to explore the value of tenecteplase and alteplase in AIS treatment.… read more here.
Keywords: tenecteplase alteplase; neurological improvement; tenecteplase showed; tenecteplase ... See more keywords
Tenecteplase vs. alteplase for treatment of acute ischemic stroke: A systematic review and meta-analysis of randomized trials
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1102463
Abstract: Background and objectives Several randomized controlled trials (RCTs) have compared tenecteplase to alteplase for treatment of acute ischemic stroke (AIS). Yet, there is no meta-analysis that includes the latest published RCTs of 2022. We sought… read more here.
Keywords: meta analysis; tenecteplase alteplase; alteplase treatment; value ... See more keywords
Tenecteplase or Alteplase Better in Patients with Acute Ischemic Stroke Due to Large Vessel Occlusion: A Single Center Observational Study
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DOI: 10.3390/medicina58091169
Abstract: Background and Objectives: The study aimed to investigate the efficacy of intravenous thrombolysis with Tenecteplase before thrombectomy for acute ischemic stroke (AIS) patients compared with previous results using Alteplase. Previous trials for Tenecteplase have indicated… read more here.
Keywords: occlusion; tenecteplase; acute ischemic; tenecteplase alteplase ... See more keywords
Recanalization before Thrombectomy in Tenecteplase vs. Alteplase-Treated Drip-and-Ship Patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Stroke"
DOI: 10.5853/jos.2018.01998
Abstract: The Extending the time for Thrombolysis in Emergency Neurological Deficits–Intra-Arterial using Tenecteplase (EXTEND-IA TNK) trial recently showed 2-fold higher early recanalization (ER) rate before mechanical thrombectomy (MT) following intravenous thrombolysis (IVT) with tenecteplase 0.25 mg/kg,… read more here.
Keywords: tenecteplase alteplase; recanalization thrombectomy; drip ship; alteplase ... See more keywords