An O-Benzyl Phosphonamidate Prodrug of Tenofovir for the Treatment of Hepatitis B Virus Infection.
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DOI: 10.1021/acs.jmedchem.2c00869
Abstract: A series of new O-(substituted benzyl) phosphoramidate prodrugs of tenofovir for the treatment of hepatitis B virus (HBV) infections have been designed and synthesized. An investigation of structure-activity relationships revealed that the compound bearing an… read more here.
Keywords: tenofovir; benzyl; hepatitis virus; treatment hepatitis ... See more keywords