A prospective real‐world study of the diffuse‐type tenosynovial giant cell tumor patient journey: A 2‐year observational analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27067
Abstract: Diffuse‐tenosynovial giant cell tumor (D‐TGCT) is a rare, locally aggressive, typically benign neoplasm affecting mainly large joints, representing a wide clinical spectrum. We provide a picture of the treatment journey of D‐TGCT patients as a… read more here.
Keywords: cell tumor; tenosynovial giant; year observational; giant cell ... See more keywords
Unusual manifestations of diffuse-type tenosynovial giant cell tumor in two patients: importance of radiologic-pathologic correlation
Sign Up to like & getrecommendations! Published in 2019 at "Skeletal Radiology"
DOI: 10.1007/s00256-019-03325-7
Abstract: Diffuse-type tenosynovial giant cell tumor (TSGCT) is a rare, locally aggressive neoplasm. It most commonly occurs in the knee, followed by the hip, and has distinctive imaging features, including mass-like foci of low T2 signal… read more here.
Keywords: giant cell; tenosynovial giant; importance radiologic; cell tumor ... See more keywords
Clinical and immunohistochemical analysis of diffuse tenosynovial giant cell tumour of the temporomandibular joint.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of oral and maxillofacial surgery"
DOI: 10.1016/j.ijom.2019.10.022
Abstract: The objective of this study was to summarize diagnostic points and treatment strategies for diffuse tenosynovial giant cell tumours (D-TSGCTs) of the temporomandibular joint (TMJ), and to evaluate the expression of proteins related to bone… read more here.
Keywords: tenosynovial giant; giant cell; temporomandibular joint; diffuse tenosynovial ... See more keywords
CHONDROID TENOSYNOVIAL GIANT CELL TUMOR OF THE TEMPOROMANDIBULAR JOINT
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.03.151
Abstract: Background Tenosynovial giant cell tumor (TGCT) is a locally aggressive tumor arising from the synovium, most commonly associated with the large joints such as the knee, but they may involve the temporomandibular joint (TMJ). Compared… read more here.
Keywords: cell tumor; giant cell; tumor; tenosynovial giant ... See more keywords
Interactions in CSF1-Driven Tenosynovial Giant Cell Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-22-1898
Abstract: The majority of cells in Tenosynovial Giant Cell Tumor (TGCT) are macrophages responding to CSF1 that is overproduced by a small number of neoplastic cells with a chromosomal translocation involving the CSF1 gene. Treatment with… read more here.
Keywords: csf1 driven; giant cell; neoplastic cells; tenosynovial giant ... See more keywords
Abstract 2020: Identification of abnormal CSF1 transcripts in tenosynovial giant cell tumors and dose-dependent increase in plasma CSF1 levels in response to pexidartinib treatment
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Trials"
DOI: 10.1158/1538-7445.am2020-2020
Abstract: Background: Tenosynovial giant cell tumors (TGCTs) are characterized by rearrangements of the colony-stimulating factor 1 (CSF1) gene. Dysregulated CSF1 may attract CSF1 receptor (CSF1R)-bearing mononuclear cells that form the bulk of the tumor. CSF1R inhibitors… read more here.
Keywords: tenosynovial giant; giant cell; plasma csf1; pexidartinib ... See more keywords
Fine Needle Aspiration Cytology of Diffuse-Type Tenosynovial Giant Cell Tumors
Sign Up to like & getrecommendations! Published in 2017 at "Acta Cytologica"
DOI: 10.1159/000457828
Abstract: Background: Tenosynovial giant cell tumor (TSGCT), also known as giant cell tumor of tendon sheath or pigmented villonodular synovitis, is the most common benign tumor of the tendon and synovium. The intra-articular diffuse type can… read more here.
Keywords: giant cell; tenosynovial giant; diffuse type; giant ... See more keywords
18F-FDG PET/CT image of tenosynovial giant cell tumor in the thoracic vertebra.
Sign Up to like & getrecommendations! Published in 2023 at "Hellenic journal of nuclear medicine"
DOI: 10.1967/s002449912558
Abstract: Diffuse-type tenosynovial giant cell tumor (D-TSGCT) is a destructive benign tumor-like proliferative disease. Diffuse-type tenosynovial giant cell tumorrarely arises from the axial skeleton. We report a case of image findings of D-TSGCT in the thoracic… read more here.
Keywords: thoracic vertebra; giant cell; 18f fdg; tenosynovial giant ... See more keywords
Pediatric Tenosynovial Giant Cell Tumor of the Flexor Hallucis Longus Tendon Sheath: A Case Report.
Sign Up to like & getrecommendations! Published in 2020 at "JBJS case connector"
DOI: 10.2106/jbjs.cc.19.00519
Abstract: CASE An otherwise healthy 13-year-old girl presented with a firm nodule on the plantar right forefoot that was tender after cheerleading. Initial workup was unremarkable, but magnetic resonance imaging revealed a multilobulated mass surrounding the… read more here.
Keywords: tenosynovial giant; giant cell; cell tumor; flexor hallucis ... See more keywords
Pexidartinib in the Management of Advanced Tenosynovial Giant Cell Tumor: Focus on Patient Selection and Special Considerations
Sign Up to like & getrecommendations! Published in 2022 at "OncoTargets and therapy"
DOI: 10.2147/ott.s345878
Abstract: Abstract Tenosynovial giant cell tumor (TGCT) is a neoplasm of the joint synovium that can have severe impacts on joint mobility, function, and quality of life. Traditionally, treatment modalities included partial or complete surgical synovectomy,… read more here.
Keywords: tenosynovial giant; giant cell; treatment; cell tumor ... See more keywords
t(1;2)-Positive Localized Tenosynovial Giant Cell Tumor With Bone Invasion
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12989
Abstract: Abstract Background: Localized tenosynovial giant cell tumor (LTGCT) is one of the most common benign soft-tissue tumors of the foot. Although pressure erosion in the adjacent bone may be seen, intraosseous invasion of LTGCT is… read more here.
Keywords: bone; tenosynovial giant; giant cell; tumor ... See more keywords