A novel isoform of Tensin1 promotes actin filament assembly for efficient erythroblast enucleation.
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DOI: 10.1182/bloodadvances.2025016100
Abstract: Key Points • A novel short TNS1 isoform (eTNS1) with a unique primate-specific start exon 1E increases late in terminal erythroid differentiation.• CRISPR-associated protein 9 deletion of eTNS1 impairs F-actin assembly in orthochromatic erythroblasts and… read more here.
Keywords: filament assembly; tensin1 promotes; novel isoform; actin filament ... See more keywords