Modeling tensional homeostasis in multicellular clusters.
Sign Up to like & getrecommendations! Published in 2017 at "International journal for numerical methods in biomedical engineering"
DOI: 10.1002/cnm.2801
Abstract: Homeostasis of mechanical stress in cells, or tensional homeostasis, is essential for normal physiological function of tissues and organs and is protective against disease progression, including atherosclerosis and cancer. Recent experimental studies have shown that… read more here.
Keywords: homeostasis; tensional homeostasis; homeostasis multicellular; modeling tensional ... See more keywords
Focal adhesion displacement magnitude is a unifying feature of tensional homeostasis.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.06.043
Abstract: Tensional homeostasis is widely recognized to exist at the length scales of organs and tissues, but the cellular length scale mechanism for tension regulation is not known. In this study, we explored whether tensional homeostasis… read more here.
Keywords: tensional homeostasis; homeostasis; focal adhesion; feature ... See more keywords
Vascular remodeling: A redox‐modulated mechanism of vessel caliber regulation
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.01.025
Abstract: ABSTRACT Vascular remodeling, i.e. whole‐vessel structural reshaping, determines lumen caliber in (patho)physiology. Here we review mechanisms underlying vessel remodeling, with emphasis in redox regulation. First, we discuss confusing terminology and focus on strictu sensu remodeling.… read more here.
Keywords: tensional homeostasis; vessel; redox; remodeling redox ... See more keywords
Reply to the 'Comment on "Tensional homeostasis at different length scales" by J. Humphrey and C. Cyron, Soft Matter, 2022, 18, DOI: 10.1039/D1SM01151K'.
Sign Up to like & getrecommendations! Published in 2022 at "Soft matter"
DOI: 10.1039/d1sm01495a
Abstract: Drs Humphrey and Cyron wrote a commentary regarding our review article entitled "Tensional homeostasis at different length scales" that was published in Soft Matter, 2020, 16, 6946-6963. These authors brought up some valid concerns to… read more here.
Keywords: homeostasis different; humphrey cyron; soft matter; homeostasis ... See more keywords
Focal Adhesion Displacement Magnitude is a Unifying Feature of Tensional Homeostasis
Sign Up to like & getrecommendations! Published in 2020 at "Acta Materialia"
DOI: 10.2139/ssrn.3582162
Abstract: Tensional homeostasis is widely recognized to exist at the length scales of organs and tissues, but the cellular length scale mechanism for tension regulation is not known. In this study, we explored whether tensional homeostasis… read more here.
Keywords: tensional homeostasis; homeostasis; focal adhesion; feature ... See more keywords
Differential Impacts on Tensional Homeostasis of Gastric Cancer Cells Due to Distinct Domain Variants of E-Cadherin
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14112690
Abstract: Simple Summary Tensional homeostasis describes the ability of cells and tissues to maintain their internal mechanical tension stable at a set point value. A breakdown of tensional homeostasis is the hallmark of disease progression, including… read more here.
Keywords: homeostasis gastric; homeostasis; gastric cancer; cancer cells ... See more keywords