M6A Methylase METTL3-mediated downregulation of TEP1 mRNA stability attenuates PDGF-BB-induced HASMC remodeling and inflammation via macrophage polarization
Sign Up to like & getrecommendations! Published in 2025 at "BMC Pediatrics"
DOI: 10.1186/s12887-025-05783-6
Abstract: Childhood asthma is a chronic inflammatory disease of the respiratory tract characterized by the contraction of smooth muscle, remodeling of the airway wall, bronchial inflammation, and obstruction, which is associated with increased airway smooth muscle… read more here.
Keywords: mettl3; tep1; macrophage polarization; pdgf induced ... See more keywords
Tep1 Regulates Yki Activity in Neural Stem Cells in Drosophila Glioma Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00306
Abstract: Glioblastoma Multiforme (GBM) is the most common form of malignant brain tumor with poor prognosis. Amplification of Epidermal Growth Factor Receptor (EGFR), and mutations leading to activation of Phosphatidyl-Inositol-3 Kinase (PI3K) pathway are commonly associated… read more here.
Keywords: drosophila glioma; stem; tep1; yki activity ... See more keywords