Tepotinib reverses ABCB1-mediated multidrug resistance in cancer cells.
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DOI: 10.1016/j.bcp.2019.05.015
Abstract: Overexpression of ABCB1 transporters plays a crucial role in mediating multidrug resistance (MDR). Therefore, it is important to inhibit ABCB1 activity in order to maintain an effective intracellular level of chemotherapeutic drugs. Tepotinib is a… read more here.
Keywords: tepotinib reverses; mediated mdr; reverses abcb1; multidrug resistance ... See more keywords