Establishing the teratogenicity of Zika and evaluating causal criteria
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DOI: 10.1007/s11229-018-1866-9
Abstract: The teratogenicity of the Zika virus was considered established in 2016, and is an interesting case because three different sets of causal criteria were used to assess teratogenicity. This paper appeals to the thesis of… read more here.
Keywords: zika evaluating; sets causal; establishing teratogenicity; teratogenicity ... See more keywords
Leaf ethanolic extract of Etlingera hemesphaerica Blume alters mercuric chloride teratogenicity during the post-implantation period in Mus musculus.
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DOI: 10.1007/s43188-019-00010-8
Abstract: This study aimed to investigate the effectiveness of leaf ethanolic extract of Etlingera hemisphaerica (LE3H) against the teratogenic effects of mercuric chloride (HgCl2) in mice (Mus musculus). Pregnant M. musculus were divided into four groups,… read more here.
Keywords: teratogenicity; ethanolic extract; mercuric chloride; hgcl2 ... See more keywords
High-Versus Low-Dose Warfarin-Related Teratogenicity: A Case Report and Systematic Review.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC"
DOI: 10.1016/j.jogc.2017.11.020
Abstract: OBJECTIVE The optimal anticoagulant therapy during pregnancy in women with mechanical heart valves remains controversial. This study highlights a case of high-dose warfarin ingestion throughout pregnancy and performed a systematic review to assess rates of… read more here.
Keywords: low dose; teratogenicity; warfarin; case ... See more keywords
Mutagenicity and teratogenicity studies of vitacoxib in rats and mice
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DOI: 10.1016/j.toxrep.2018.08.007
Abstract: Vitacoxib is a new drug candidate for treatment of inflammation, pain and fever as selective cyclooxygenase-2 inhibitors. In the current study, the mice sperm abnormality, mammalian erythrocyte micronucleus and in vivo chromosome aberration, and teratogenicity… read more here.
Keywords: studies vitacoxib; mutagenicity teratogenicity; teratogenicity; teratogenicity studies ... See more keywords
embryoTox: Using Graph-Based Signatures to Predict the Teratogenicity of Small Molecules
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c00824
Abstract: Teratogenic drugs can lead to extreme fetal malformation and consequently critically influence the fetus's health, yet the teratogenic risks associated with most approved drugs are unknown. Here, we propose a novel predictive tool, embryoTox, which… read more here.
Keywords: based signatures; using graph; embryotox using; graph based ... See more keywords
Prescribing antidepressants and anxiolytic medications to pregnant women: comparing perception of risk of foetal teratogenicity between Australian Obstetricians and Gynaecologists, Speciality Trainees and upskilled General Practitioners
Sign Up to like & getrecommendations! Published in 2020 at "BMC Pregnancy and Childbirth"
DOI: 10.1186/s12884-020-03293-0
Abstract: Background Depression and anxiety are common disorders, however their occurrence during pregnancy has the potential to significantly impact the health and wellbeing of both mother and child [1, 2]. Negative outcomes of mental health disorders… read more here.
Keywords: depression; risk; pregnancy; teratogenicity ... See more keywords